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Anti-PRKDC / DNA-PKcs Antibody (C-Terminus) LS-C64819

Catalog Size Price
LS-C64819-20 20 µg Unavailable

Most Popular PRKDC / DNA-PKcs Antibodies

Anti-PRKDC / DNA-PKcs Antibody (phospho-Thr2609) IHC-plus™ LS-B409
Rabbit Polyclonal to Human PRKDC / DNA-PKcs
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-PRKDC / DNA-PKcs Antibody (aa4061-4110) IHC-plus™ LS-B6857
Rabbit Polyclonal (IgG) to Human PRKDC / DNA-PKcs
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-PRKDC / DNA-PKcs Antibody (aa4078-4128) LS-C290617
Goat Polyclonal to Human PRKDC / DNA-PKcs
Human, Mouse, Rat, Bovine, Guinea pig, Pig
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-PRKDC / DNA-PKcs Antibody (phospho-Thr2609) LS-C336068
Rabbit Polyclonal (IgG) to Human PRKDC / DNA-PKcs
Human
Western blot
Unconjugated
Western blot Image
Anti-PRKDC / DNA-PKcs Antibody (phospho-Thr2647) LS-C368485
Rabbit Polyclonal to Human PRKDC / DNA-PKcs
Human, Monkey
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed
Rabbit Polyclonal to Human PRKDC / DNA-PKcs
Human
Western blot, Immunoprecipitation
Unconjugated

Details

Human PRKDC / DNA-PKcs
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • Immunoprecipitation

Specificity and Use

PRKDC / DNA-PKcs antibody was raised against the epitope maps to a region between residues 4075 and the C-terminus (residue 4128) of human DNA-Dependent Protein Kinase, catalytic subunit using the numbering given in entry NP_008835.5 (GeneID 5591).
C-Terminus
Species cross-reactivity: Human. Reactivity with DNA-PKcs from mouse and chicken is likely owing to conservation of sequence between these orthologs and human DNA-PKcs at the site to which the epitope maps. Reactivity with DNA-PKcs from X. laevis is possible but less likely.
Suitable for use in Western Blot and Immunoprecipitation.

Packaging

TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide.
For research use only.

About PRKDC / DNA-PKcs

P78527 NM_006904 NP_008835.5

PRKDC Antibody, DNA-PK Antibody, DNAPK Antibody, DNPK1 Antibody, HYRC Antibody, HYRC1 Antibody, p350 Antibody, Scid Antibody, XRCC7 Antibody, DNA-PK catalytic subunit Antibody, DNA-PKcs Antibody, p460 Antibody, DNA-dependent protein kinase catalytic subunit Antibody

Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step.

Requested From: 
Date Requested: 6/29/2017

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