Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse, Rat, Bovine, Xenopus (tested or 100% immunogen sequence identity)
IHC - Paraffin (10 µg/ml)
Specificity and Use
PPP1R8 / Rnase E antibody was raised against synthetic peptide corresponding to a region within amino acids 288 and 351 of NIPP1 (SwissProt Q12972). Percent identity by BLAST analysis: Human, Mouse, Porcine, Rat, Xenopus, Bovine (100%).
Antibody reactive against peptide, detects immunogen.
PBS, pH 7, 40% Glycerol, 0.01% Thimerosal
Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.
PPP1R8 Antibody, ARD-1 Antibody, ARD1 Antibody, Activator of RNA decay Antibody, NIPP-1 Antibody, NIPP1 Antibody, Nuclear subunit of PP-1 Antibody, PRO2047 Antibody, RNase E Antibody
Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions.