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Anti-PIK3R2 / p85 Beta Antibody (clone T15) LS-C43327

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Most Popular PIK3R2 / p85 Beta Antibodies

Anti-PIK3R2 / p85 Beta Antibody (clone T15) LS-C43327
Mouse Monoclonal [clone T15] (IgG1) to Bovine PIK3R2 / p85 Beta
Bovine, Human, Monkey
IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated
Anti-PIK3R2 / p85 Beta Antibody LS-C124372
Mouse Monoclonal (IgG1) to Bovine PIK3R2 / p85 Beta
Bovine, Human, Monkey
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated
Anti-PIK3R2 / p85 Beta Antibody (aa447-461) LS-C312832
Rabbit Polyclonal (IgG) to Human PIK3R2 / p85 Beta
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Pig, Sheep
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

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Mouse Monoclonal [clone T15] (IgG1) to Bovine PIK3R2 / p85 Beta
Bovine, Human, Monkey
IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated

Details

Bovine PIK3R2 / p85 Beta
Mouse
Bovine, Human, Monkey (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [T15]
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Frozen
  • Western blot (1:500 - 1:1000)
  • Immunoprecipitation (10 µg/ml)

Specificity and Use

PIK3R2 / p85 Beta antibody was raised against balculovirus expressed (Recombinant) Bovine P85 beta subunit of P13 kinase.
Recognizes the HLA-B27 alloantigen. Reacts with the peripheral blood lymphocytes of 47/47 individuals conventionally typed as HLA-B27 + and precipitates cell surface molecules of 43 and 12 kD, corresponding to the HLA Class 1 heavy chain and beta 2 microglobulin. Affinity studies by Scatchard analysis showed that this has a higher affinity for HLA-B27 (9.7 x 108 M-1) than for HLA B7 (9.5 x 107 M-1). Subjects Expected Fluorescence Intensity Heterozygous HLA-B27+ Strong Homozygous HLA-B27+ Strong Heterozygous HLA-B7+ Faint Non B27, Non B7 Negative.

Packaging

0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About PIK3R2 / p85 Beta

O00459 NM_005027 NP_005018.1

PIK3R2 Antibody, p85 Antibody, p85B Antibody, p85-BETA Antibody, PI3K regulatory subunit beta Antibody, MPPH Antibody, PI3-kinase subunit p85-beta Antibody

Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology.

Requested From: United States
Date Requested: 12/10/2016

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