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Anti-PIK3R2 / p85 Beta Antibody (clone T15) LS-C43327

Catalog	Size	Price
LS-C43327-100	100 µg (1 mg/ml)	Unavailable

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63 PIK3R2 / p85 Beta Antibodies

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Antibody:	Mouse Monoclonal [clone T15] (IgG1) to Bovine PIK3R2 / p85 Beta
Reactivity:	Bovine, Human, Monkey
Application:	IHC - Frozen, Western blot, Immunoprecipitation
Format:	Unconjugated

Anti-PIK3R2 / p85 Beta Antibody (aa1-30) LS-C101099

Antibody:	Rabbit Polyclonal to Human PIK3R2 / p85 Beta
Reactivity:	Human
Application:	IHC - Paraffin, Western blot
Format:	Unconjugated

Anti-PIK3R2 / p85 Beta Antibody LS-C124372

Antibody:	Mouse Monoclonal (IgG1) to Bovine PIK3R2 / p85 Beta
Reactivity:	Bovine, Human, Monkey
Application:	IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Format:	Unconjugated

Anti-PIK3R2 / p85 Beta Antibody (Tyr467) IHC-plus™ LS-B9129

Antibody:	Rabbit Polyclonal to Human PIK3R2 / p85 Beta
Reactivity:	Human
Application:	IHC - Paraffin, Western blot
Format:	Unconjugated

Anti-PIK3R2 / p85 Beta Antibody (aa447-461) LS-C312832

Antibody:	Rabbit Polyclonal (IgG) to Human PIK3R2 / p85 Beta
Reactivity:	Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Pig, Sheep
Application:	IHC - Paraffin, Western blot
Format:	Unconjugated

Antibody:	Mouse Monoclonal [clone T15] (IgG1) to Bovine PIK3R2 / p85 Beta
Reactivity:	Bovine, Human, Monkey
Application:	IHC - Frozen, Western blot, Immunoprecipitation
Format:	Unconjugated

Details

Target:	Bovine PIK3R2 / p85 Beta
Host:	Mouse
Reactivity:	Bovine, Human, Monkey (tested or 100% immunogen sequence identity)
Clonality:	IgG1 Monoclonal [T15]
Conjugations:	Unconjugated
Purification:	Protein G purified
Modifications:	Unmodified

Applications

Approved:

IHC - Frozen
Western blot (1:500 - 1:1000)
Immunoprecipitation (10 µg/ml)

Specificity and Use

Immunogen:

Balculovirus expressed (Recombinant) Bovine P85 beta subunit of P13 kinase.

Specificity:

Recognizes the HLA-B27 alloantigen. Reacts with the peripheral blood lymphocytes of 47/47 individuals conventionally typed as HLA-B27 + and precipitates cell surface molecules of 43 and 12 kD, corresponding to the HLA Class 1 heavy chain and beta 2 microglobulin. Affinity studies by Scatchard analysis showed that this has a higher affinity for HLA-B27 (9.7 x 108 M-1) than for HLA B7 (9.5 x 107 M-1). Subjects Expected Fluorescence Intensity Heterozygous HLA-B27+ Strong Homozygous HLA-B27+ Strong Heterozygous HLA-B7+ Faint Non B27, Non B7 Negative.

Packaging

Presentation:	0.09% sodium azide.
Storage:	Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
Restrictions:	For research use only.

About PIK3R2 / p85 Beta

Uniprot: O00459 NCBI: NM_005027 NP_005018.1

Synonyms: PIK3R2 Antibody, p85 Antibody, p85B Antibody, p85-BETA Antibody, PI3K regulatory subunit beta Antibody, MPPH Antibody, PI3-kinase subunit p85-beta Antibody

Description: Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology.

(More About PIK3R2 / p85 Beta)

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Date Requested: 10/17/2017

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