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Anti-PIAS4 / PIASY Antibody (Asp488) LS-C176344

Catalog Size Price
LS-C176344-100 100 µl Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human PIAS4 / PIASY
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated

Details

Human PIAS4 / PIASY
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot

Specificity and Use

PIAS4 / PIASY antibody was raised against synthetic peptide around Asp488 of human PIAS4 / PIASY
Asp488
Human PIAS4 / PIASY

Packaging

PBS, pH 7.2, 0.05% sodium azide
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only.

About PIAS4 / PIASY

Q8N2W9 NM_015897 NP_056981.2

PIAS4 Antibody, E3 SUMO-protein ligase PIAS4 Antibody, PIAS-gamma Antibody, ZMIZ6 Antibody, Piasg Antibody, PIASY Antibody

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168.

Immunohistochemistry

Immunohistochemistry
IHC of PIAS4 (D488) pAb in paraffin-embedded human lung carcinoma tissue.

Western blot

Western blot
Western blot of PIAS4 (D488) pAb in extracts from Jurkat cells.

Requested From: 
Date Requested: 10/20/2017

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