Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Phosphoserine antibody was raised against phosphoserine containing proteins.
Recognizes proteins containing phosphorylated serine residues (pSer). Recognition of pSer containing proteins by this antibody is independent of neighboring amino acids and species of origin of the phosphorylated protein. Shows no significant cross-reactivity to proteins phosphorylated on threonine or tyrosine residues.
Suitable for use in ELISA, Western Blot and Immunoprecipitation. ELISA: 0.1-1.0 ug. ml. Western Blot: 1-2 ug/ml. Milk-derived blocking solutions reportedly contain phosphoproteins that may inhibit phosphoamino acid antibody binding and therefore should be avoided. A 3% BSA solution may be used. Immunoprecipitation: 3-5 ug/IP reaction. Positive control: NIH 3T3 cells (+/-TPA), K562 cells, EGF-stimulated A431 cell lysates.