Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Hamster Polyclonal (IgG) to Mouse PDCD1 / CD279 / PD-1
Mouse PDCD1 / CD279 / PD-1
Mouse (tested or 100% immunogen sequence identity)
Protein G purified
Flow Cytometry (2 µg/10E6 cells)
Specificity and Use
PD-1 cDNA transfectant.
PD1 monoclonal antibody reacts with mouse PD-1 (programmed death-1), a 55 kD member of the Ig superfamily that has been demonstrated to play a key role in the regulation of immune response and peripheral tolerance. PD1 is expressed on activated T and B l.
PDCD1 / CD279 / PD-1 is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure.