Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
IHC - Paraffin (1:50)
Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
PBK / TOPK antibody was raised against synthetic peptide (KLH-coupled) corresponding to amino acids at the carboxy-terminus of human PBK/TOPK.
Detects endogenous levels of total PBK/TOPK protein.
Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry. Western Blot: 1:1000. Immunohistochemistry: (Paraffin) 1:50. IHC Protocol: Citrate/TBST. Immunocytochemistry: (IF) 1:100.
10 mM HEPES-Sodium, pH 7.5, 150 mM NaCl, 100 ug/ml BSA, 50% Glycerol
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
TOPK is a TOPK protein kinase which may be associated with cell signaling in lymphokine-activated killer T (T-LAK) cells and spermatogenesis. Studies suggest that mitotic phosphorylation is required for its catalytic activity. Similar to MEK3/MAP2K3 and MKK6/MAP2K6, activated TOPK phosphorylates the MAP kinase p38. At least two mRNA variants have been identified - a major full-length form and a minor spliced form at the 5'-site, both encoding the same protein.