Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, ELISA
Human, Mouse, Rat, Hamster, Xenopus, Drosophila (tested or 100% immunogen sequence identity)
Protein G purified
IHC - Paraffin
IHC - Frozen
Western blot (1:1000 - 1:5000)
Specificity and Use
PARP1 antibody was raised against human PARP.
Recognizes human poly (ADP-ribose) polymerase (PARP). Species cross-reactivity: hamster, mouse, drosophila, xenopus, rat.
Suitable for use in ELISA, Immunohistochemistry (frozen and paraffin), Immunoprecipitation, and Western blot: 1:1000-1:5000. Immunohistochemistry (paraffin): Requires antigen retrieval using heat treatment prior to staining of paraffin sections.
0.09% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR.