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Anti-PARP1 Antibody (C-Terminus) LS-C17215

Catalog	Size	Price
LS-C17215-100	100 µl	Unavailable

Related Products

325 PARP1 Antibodies

Most Popular PARP1 Antibodies

Anti-PARP1 Antibody (aa197-214) LS-C9488

Antibody:	Rabbit Polyclonal to Human PARP1
Reactivity:	Human, Monkey, Dog, Hamster, Rabbit
Application:	ICC, Western blot, Immunoprecipitation, ELISA
Format:	Unconjugated

Anti-PARP1 Antibody (N-Terminus) IHC-plus™ LS-B1243

Antibody:	Rabbit Polyclonal to Human PARP1
Reactivity:	Human, Mouse, Rat
Application:	IHC - Paraffin, Western blot
Format:	Unconjugated

Anti-PARP1 Antibody (N-Terminus) IHC-plus™ LS-B3395

Antibody:	Rabbit Polyclonal to Human PARP1
Reactivity:	Human, Mouse, Rat
Application:	IHC - Paraffin, Western blot
Format:	Unconjugated

Anti-PARP1 Antibody (clone A6.4.12) IHC-plus™ LS-B3432

Antibody:	Mouse Monoclonal [clone A6.4.12] (IgG1) to Human PARP1
Reactivity:	Human, Mouse, Rat, Hamster, Xenopus, Drosophila
Application:	IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, ELISA
Format:	Unconjugated

Anti-PARP1 Antibody (clone 10H) LS-C146823

Antibody:	Mouse Monoclonal [clone 10H] (IgG3,k)
Application:	ICC, Western blot, Immunoprecipitation, ELISA
Format:	Unconjugated

Antibody:	Rabbit Polyclonal (IgG) to Human PARP1
Reactivity:	Human
Application:	IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Format:	Unconjugated

Details

Target:	Human PARP1
Host:	Rabbit
Reactivity:	Human (tested or 100% immunogen sequence identity)
Clonality:	IgG Polyclonal
Conjugations:	Unconjugated
Purification:	Protein A purified
Modifications:	Unmodified

Applications

Approved:

IHC - Paraffin (1:50)
ICC
Immunofluorescence
Western blot (1:1000)
Flow Cytometry (1:25)
ELISA

Specificity and Use

Immunogen:	PARP1 antibody was raised against synthetic peptide (KLH coupled) corresponding to C-terminal residues adjacent to Asp214 in human PARP.
Epitope:	C-Terminus
Specificity:	Detects endogenous levels of the large fragment (89kD) of human PARP produced by caspase cleavage. Does not react with full length PARP.
Usage:	Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry. Western Blot: 1:1000. Immunohistochemistry (Paraffin): 1:50. Immunocytochemistry (IF): 1:200. Flow Cytometry: 1:25.

Packaging

Presentation:	10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol. No preservative added.
Storage:	Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
Restrictions:	For research use only.

About PARP1

Uniprot: P09874 NCBI: NM_001618 NP_001609.2

Synonyms: PARP1 Antibody, ADPRT Antibody, ADP-ribosyltransferase NAD(+) Antibody, Adp-ribosyltransferase Antibody, ADPRT1 Antibody, ARTD1 Antibody, ADPRT 1 Antibody, Poly(ADP-ribose) synthetase Antibody, Poly(ADP-ribosyl)transferase Antibody, PARP Antibody, Poly [ADP-ribose] polymerase 1 Antibody, PADPRT-1 Antibody, PARP-1 Antibody, Poly (ADP-ribose) polymerase 1 Antibody, Poly(ADP-ribose) polymerase Antibody, Poly[ADP-ribose] synthase 1 Antibody, PPOL Antibody

Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR.

(More About PARP1)

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Date Requested: 6/28/2017

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