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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PARK2 / Parkin 2 Antibody (aa1‑50) IHC‑plus™ LS‑B7045
Note: This antibody replaces LS-C118549
Parkin 2 antibody LS-B7045 is an unconjugated rabbit polyclonal antibody to Parkin 2 (PARK2) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B7045-50
50 µl
Unavailable

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Product Description

Parkin 2 antibody LS-B7045 is an unconjugated rabbit polyclonal antibody to Parkin 2 (PARK2) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
About PARK2 / Parkin 2
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5, TOMM20, USP30, ZNF746 and AIMP2. Mediates monoubiquitination as well as 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. O60260 NM_004562 NP_004553.2

PARK2 Antibody, AR-JP Antibody, LPRS2 Antibody, Parkin Antibody, PDJ Antibody, Parkinson disease protein 2 Antibody, PRKN Antibody


Specifications

Target
Human PARK2 / Parkin 2
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:5000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide from human Parkin (aa1-50).
Epitope
aa1-50
Specificity
Parkin Antibody detects endogenous levels of total Parkin protein.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-PARK2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7045 dilution 1:100.
Anti-PARK2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7045 dilution 1:100.

Western blot

Western blot of extracts from Jurkat cells, using Parkin Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from Jurkat cells, using Parkin Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

Anti-PARK2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7045 dilution 1:100.
Anti-PARK2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7045 dilution 1:100.

Western blot

Western blot of extracts from Jurkat cells, using Parkin Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from Jurkat cells, using Parkin Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

Anti-PARK2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7045 dilution 1:100.
Anti-PARK2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7045 dilution 1:100.

Western blot

Western blot of extracts from Jurkat cells, using Parkin Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from Jurkat cells, using Parkin Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

Anti-PARK2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7045 dilution 1:100.
Anti-PARK2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7045 dilution 1:100.

Western blot

Western blot of extracts from Jurkat cells, using Parkin Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from Jurkat cells, using Parkin Antibody. The lane on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/21/2018

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