Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey, Mouse, Rat, Guinea pig
(tested or 100% immunogen sequence identity)
Western blot (1:1000)
PAK2 antibody was raised against synthetic peptide (KLH coupled) corresponding to the N-terminal region of human PAK2.
Detects endogenous levels of total human PAK2 protein. Does not cross-react with PAK1, PAK3 or PAK4-6. Species cross-reactivity: Guinea pig, monkey, mouse, rat.
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1:1000. Western blot analysis of extracts from HeLa, NIH/3T3, C6,. COS, guinea pig neutrophils (GPN) and HEK293 cells recognizes a 61kD protein. Immunoprecipitation: 1:100.
10 mM HEPES-Sodium, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 50% Glycerol
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth.