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Anti-NTRK2 / TRKB Antibody LS-C150263

Catalog Size Price
LS-C150263-25 25 µg Unavailable
LS-C150263-100 100 µg (0.2 mg/ml) Unavailable

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100% Guaranteed
Goat Polyclonal (IgG) to Mouse NTRK2 / TRKB
IHC, Western blot, ELISA


Mouse NTRK2 / TRKB
Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • IHC (2 - 5 µg/ml)
  • Western blot (0.1 - 0.2 µg/ml)
  • ELISA (50 µg/ml)

Specificity and Use

NTRK2 / TRKB antibody was raised against purified, NS0-derived, recombinant mouse TrkB (rmTrkB) extracellular domain.
Mouse TrkB extracellular domain.
Blocking of receptor-ligand interaction-Approximately 0.5-2 µg/ml of this antibody will block 50% of the binding of 5 ng/ml of rhBDNF to immobilized rmTrkB/Fc chimera (100 ul of a 2 µg/ml solution was coated in each well) in a functional ELISA. At 50 µg/ml, this antibody will achieve 100% blocking in the assay. Direct ELISA-This antibody can be used at 0.5-1.0 µg/ml with the appropriate secondary reagents to detect mouse TrkB. The detection limit for rmTrkB is approximately 0.1 ng/well. Western blot-This antibody can be used at 0.1-0.2 µg/ml with the appropriate secondary reagents to detect mouse TrkB. The detection limit for rmTrkB is approximately 2 ng/lane under non-reducing and reducing conditions. Immunohistochemistry-This antibody will detect TrkB in cells and tissues. The working dilution is 2-5 µg/ml.


Lyophilized from 0.2 um sterile-filtered solution in PBS, 5% trehalose
Reconstitute at 0.2 mg/mL in sterile PBS
Store at -20°C.
For research use only.

About NTRK2 / TRKB

Q16620 NM_006180 NP_006171.2

NTRK2 Antibody, gp145-TrkB Antibody, Trk-B Antibody, TRKB Antibody, Tropomyosin-related kinase B Antibody, TrkB tyrosine kinase Antibody, Tyrosine kinase receptor B Antibody

Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2.

Requested From: 
Date Requested: 2/25/2018

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