LSBio The Immunohistochemistry Antibody Company
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-NQO1 Antibody (clone A180) LS-C188428

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NQO1 Antibodies

Anti-NQO1 Antibody (clone A180) IHC-plus™ LS-B116
Mouse Monoclonal [clone A180] (IgG1) to Human NQO1
Human, Rat, Dog, Primate
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-NQO1 Antibody (aa134-146) IHC-plus™ LS-B8354
Goat Polyclonal to Human NQO1
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-NQO1 Antibody (aa263-274) IHC-plus™ LS-B11145
Goat Polyclonal to Human NQO1
Human, Monkey, Mouse, Dog, Rabbit
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone A180] (IgG1) to Human NQO1
Human, Rat
IHC - Paraffin, Western blot, Immunoprecipitation (applications tested for the base form of this product only)
Unconjugated

Details

Human NQO1
Mouse
Human, Rat (tested or 100% immunogen sequence identity)
Mouse
IgG1 Monoclonal [A180]
Unconjugated. Also available conjugated with HRP.
Protein G purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot (1:100 - 1:1000)
  • Immunoprecipitation
  • (applications tested for the base form of this product only)

Specificity and Use

NQO1 antibody was raised against purified recombinant human NQO1.
Recognizes human NQO1 (NAD(P)H: quinone oxidoreductase 1), a 31kD cytosolic flavoenzyme and member of the NAD(P)H dehydrogenase (quinone) family, involved in detoxification, which catalyzes the two-electron reduction of quinones to hydroquinones. NQO1 is expressed in a wide range of tissues and is overexpressed in many human tumors including lung, brain, liver, colon and breast. The ability of NQO1 to bioactivate anti-tumor quinones including mitomycin C and diaziquone, has become a focus area for chemotherapeutic studies. Mutations in the NQO1 gene are associated with an increased risk of certain cancers, and an increased risk of leukaemia has been associated with diminished NQO1 activity and the NQO1 *2 allele. Clone A180 detects endogenous levels of total NQO1, and does not cross-react with NQO2. Clone A180 is reported as suitable for use in immunofluorescence studies.

Packaging

PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About NQO1

P15559 NM_000903 NP_000894.1

NQO1 Antibody, Azoreductase Antibody, DHQU Antibody, DT-diaphorase Antibody, Dioxin-inducible 1 Antibody, DIA4 Antibody, Diaphorase-4 Antibody, NAD(P)H:quinone oxireductase Antibody, Phylloquinone reductase Antibody, QR1 Antibody, Menadione reductase Antibody, NMOR1 Antibody, NMORI Antibody, DTD Antibody, Quinone reductase 1 Antibody

NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species.

Requested From: United States
Date Requested: 12/11/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number