The Immunohistochemistry Antibody Company
|Human, Mouse, Rat, Bovine, Sheep, Primate (tested or 100% immunogen sequence identity)|
|NOX4 antibody was raised against a synthetic peptide made to a region within residues 100-200 of the human NOX4 protein sequence. [Swiss-Prot# Q9NPH5]|
|The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested. By Western Blot this antibody recognizes a band at ~67 kD, representing isoform 1.|
|Tris-citrate/phosphate, pH 7-8|
|Store at 4°C. Do not freeze.|
|For research use only.|
NOX4 Antibody, Kidney oxidase-1 Antibody, KOX Antibody, RENOX Antibody, KOX-1 Antibody, NADPH oxidase 4 Antibody, Renal NAD(P)H-oxidase AntibodyConstitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.