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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NOTCH1 Antibody (aa19‑526) LS‑C126049
Antibody
NOTCH1 antibody LS-C126049 is an unconjugated mouse monoclonal antibody to human NOTCH1. Validated for Flow.
Catalog
Size
Price
LS-C126049-100
100 µg
Unavailable
LS-C126049-500
500 µg
Unavailable

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Product Description

NOTCH1 antibody LS-C126049 is an unconjugated mouse monoclonal antibody to human NOTCH1. Validated for Flow.
About NOTCH1
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. P46531 NM_017617 NP_060087.3

NOTCH1 Antibody, Notch 1 Antibody, TAN1 Antibody


Specifications

Target
Human NOTCH1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry (25 µg/ml)
Immunogen
NOTCH1 antibody was raised against nS0-derived, recombinant human Notch-1 aa 19-526; P46531.
Epitope
aa19-526
Specificity
Recognizes human Notch-1.
Usage
Suitable for use in Flow cytometry: 25 ug/ml.
Presentation
Lyophilized from 0.2 um sterile-filtered solution, PBS, 5% trehalose
Reconstitution
Sterile 40-50% glycerol, PBS.
Storage
Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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