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Anti-NOD2 / CARD15 Antibody (aa28-301) LS-C73659

Catalog Size Price
LS-C73659-100 100 µl Unavailable

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100% Guaranteed
Mouse Monoclonal (IgG1) to Human NOD2 / CARD15
Human
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated

Details

Human NOD2 / CARD15
Mouse
Human (tested or 100% immunogen sequence identity)
Primate (at least 90% immunogen sequence identity)
IgG1 Monoclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot
  • Immunoprecipitation

Specificity and Use

NOD2 / CARD15 antibody was raised against recombinant human NOD2 protein corresponding to residues 28-301.
aa28-301
This antibody is specific for NOD2 protein. Species cross-reactivity: This antibody reacts with human protein. Other species have not been tested.
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Western Blot: Tested on NOD2 transfected 293T lysates and HT29 human lysates. Endogenous detection has some background. Immunohistochemistry: Paraffin.

Packaging

Tris-glycine buffer, 150 mM sodium chloride, 0.05% sodium azide.
For research use only.

About NOD2 / CARD15

Q9HC29 NM_022162 NP_071445.1

NOD2 Antibody, BLAU Antibody, CARD15 Antibody, ACUG Antibody, NOD-like receptor C2 Antibody, NOD2B Antibody, NLRC2 Antibody, IBD1 Antibody, CLR16.3 Antibody, PSORAS1 Antibody

Recognizes muramyl dipeptide (MDP) constituents of bacterial peptidoglycans and plays a key role in gastrointestinal immunity: upon stimulation, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling, leading to activate the transcription of hundreds of genes involved in immune response.

Requested From: 
Date Requested: 10/17/2017

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