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Anti-NLRP2 / NALP2 Antibody (aa144-159) LS-C148283

Catalog Size Price
LS-C148283-50 50 µl Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human NLRP2 / NALP2
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation


Human NLRP2 / NALP2
Human (tested or 100% immunogen sequence identity)


  • IHC - Paraffin (1:1000 - 1:5000)
  • IHC - Frozen
  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation (1:50 - 1:200)

Specificity and Use

NLRP2 / NALP2 antibody was raised against a synthetic peptide corresponding to amino acids 144-159 (LGKEVFKGKKPDKDNR) of human NALP2, GenBank no. gi|8923473|ref|NP_060322.1|. Percent identity by BLAST analysis: Human, Gorilla (100%).
Detected NALP2 at approx. 110 kD in THP-1 cells. Performs similarly to the NALP2/PAN1/PYPAF2 which is cited in Bruey et al, 2004. The two antibodies are made against different portions of the NALP2 protein.


Antiserum, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About NLRP2 / NALP2

Q9NX02 NM_017852 NP_060322.1

NLRP2 Antibody, CLR19.9 Antibody, PAN1 Antibody, NALP2 Antibody, NBS1 Antibody, PYPAF2 Antibody

Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

Western blot

Western blot
Western blot of NALP2 (PAN1/PYPAF2) in differentiated THP-1 cells following IFN (interferon)

Requested From: 
Date Requested: 3/23/2018

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