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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NGFRAP1 / NADE / Bex Antibody (Internal) LS‑C16680
Bex antibody LS-C16680 is an unconjugated rabbit polyclonal antibody to Bex (NGFRAP1 / NADE) from human and mouse. Validated for WB.
Antibody
Catalog
Size
Price
LS-C16680-100
100 µg
$515

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Product Description

Bex antibody LS-C16680 is an unconjugated rabbit polyclonal antibody to Bex (NGFRAP1 / NADE) from human and mouse. Validated for WB.

Specifications

Target
Human NGFRAP1 / NADE / Bex
Synonyms
NGFRAP1, Bex, BEX3, DXS6984E, HGR74, NADE, Protein BEX3, Brain expressed, X-linked 3
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Ion exchange chromatography
Modifications
Unmodified
Applications
  • Western blot
Immunogen
Peptide corresponding to 14 amino acids near the middle of human NADE (GenBank accession no. NP_996798).
Epitope
Internal
Specificity
Recognizes human NADE. Species cross-reactivity: Mouse.
Usage
Can be used for detection of NADE by Western blot at 0.5 to 2 ug/ml. Despite its predicted molecular weight, NADE migrates at ~23kD in SDS-PAGE.
Presentation
PBS, pH 7.4, 0.02% Sodium Azide
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
About NGFRAP1 / NADE / Bex
The p75 neurotrophin receptor (p75NTR) is a member of the tumor necrosis receptor superfamily and can mediate cell death and cell survival in response to nerve growth factor (NGF). The p75NTR-associated cell death executor (NADE) mediates apoptosis by interacting with the cell death domain of p75NTR following the binding of NGF by p75NTR. Recent studies have shown that NADE also interacts with second mitochondria-derived activator of caspase (Smac). Q00994 NM_014380 NP_055195.1


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Requested From: United States
Date Requested: 10/21/2018

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