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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NGFRAP1 / NADE / Bex

nerve growth factor receptor (TNFRSF16) associated protein 1

The p75 neurotrophin receptor (p75NTR) is a member of the tumor necrosis receptor superfamily and can mediate cell death and cell survival in response to nerve growth factor (NGF). The p75NTR-associated cell death executor (NADE) mediates apoptosis by interacting with the cell death domain of p75NTR following the binding of NGF by p75NTR. Recent studies have shown that NADE also interacts with second mitochondria-derived activator of caspase (Smac). Co-expression of NADE and Smac promotes TRAIL-induced apoptosis and inhibits XIAP-mediated Smac ubiquitization. It has been suggested that it is this interaction between NADE and Smac that allows apoptosis to proceed. Finally, although initially discovered as an mRNA expressed in ovarian granulosa cells, NADE has been suggested to play a role in the neuronal death seen in epileptic brain damage.

Gene Name: nerve growth factor receptor (TNFRSF16) associated protein 1
Synonyms: NGFRAP1, Bex, BEX3, DXS6984E, HGR74, NADE, Protein BEX3, Brain expressed, X-linked 3
Target Sequences: NM_014380 NP_055195.1 Q00994

Viewing 1-18 of 18 items
NGFRAP1 / NADE / Bex Antibody - Anti-NGFRAP1 / NADE antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
Select
Rabbit Polyclonal to Human NGFRAP1 / NADE / Bex
Human
IF, IHC, WB
Unconjugated
100µl   $385.00
NGFRAP1 / NADE / Bex Antibody - Immunofluorescence analysis of MCF7 cells.
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
NGFRAP1 / NADE / Bex Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Human
ELISA, IHC, IHC-P
Unconjugated
50µl   $235.00; 100µl   $285.00
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Mouse, Human
IF, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
NGFRAP1 / NADE / Bex Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using NGFRAP1 Polyclonal Antibody at dilution of 1:40.
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20µl   0.6mg/ml   $205.00; 60µl   0.6mg/ml   $235.00; 120µl   0.6mg/ml   $295.00; 200µl   0.6mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Human
ELISA, WB
Unconjugated
100µg   $355.00
Select
Rabbit Polyclonal to Human NGFRAP1 / NADE / Bex
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Human
ELISA, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human NGFRAP1 / NADE / Bex
Mouse, Human
WB
Unconjugated
100µg   $530.00
NGFRAP1 / NADE / Bex Antibody - NGFRAP1 Antibody western blot of A375 cell line lysates (35 ug/lane). The NGFRAP1 antibody detected the NGFRAP1 protein (arrow).
Select
Rabbit Polyclonal to Human NGFRAP1 / NADE / Bex
Human
WB
Unconjugated
400µl   $325.00
Select
Goat Polyclonal to Human NGFRAP1 / NADE / Bex
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
Peptide-ELISA
Unconjugated
100µg   0.5mg/ml   $335.00

Viewing 1-18 of 18 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).