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Anti-NF2 / Merlin Antibody (phospho-Ser518) LS-C191037

Ordering

Wt. Vol. Conc. Price
50 µg - - $485

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Rabbit Polyclonal (IgG) to Human NF2 / Merlin
Human, Mouse, Rat
Western blot
Unconjugated

Details

Human NF2 / Merlin
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Affinity purified

Applications

Western blot (1:500 - 1:1000)

Specificity and Use

NF2 / Merlin antibody was raised against synthetic phosphopeptide corresponding to human Merlin around the phosphorylation site of serine 518 (R-L-pS-M-E).
pSer518
Human Merlin, phosphorylated at Ser518. Species Crossreactivity: mouse and rat.

Packaging

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at 12 months.
For research use only.

About NF2 / Merlin

P35240 NM_000268 NP_000259.1

NF2 Antibody, ACN Antibody, BANF Antibody, Moesin-ezrin-radixin like Antibody, Neurofibromin 2 (merlin) Antibody, Neurofibromin-2 Antibody, SCH Antibody, Merlin Antibody, Schwannomerlin Antibody, Schwannomin Antibody

Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity.

Requested From: United States
Date Requested: 7/28/2015

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