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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NEDD8 Antibody (N‑Terminus) LS‑C9223
Antibody
NEDD8 antibody LS-C9223 is an unconjugated rabbit polyclonal antibody to human NEDD8. Validated for ELISA and WB.
Catalog
Size
Price
LS-C9223-100
100 µg
Unavailable

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Product Description

NEDD8 antibody LS-C9223 is an unconjugated rabbit polyclonal antibody to human NEDD8. Validated for ELISA and WB.
About NEDD8
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Q15843 NM_006156 NP_006147.1

NEDD8 Antibody, NEDD-8 Antibody, Neddylin Antibody, Ubiquitin-like protein Nedd8 Antibody


Specifications

Target
Human NEDD8
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Purified
Modifications
Unmodified
Applications
  • Western blot (1 - 3 µg/ml)
  • ELISA (0.1 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
NEDD8 antibody was raised against synthetic peptide derived from the N-terminal sequence of human NEDD8.
Epitope
N-Terminus
Specificity
Specific for the human NEDD8 protein. Reactivity has been confirmed with EGF-stimulated A431 cell lysate.
Usage
Suitable for use in ELISA, Western Blot. ELISA: 0.1-1.0 ug/ml. Western Blot: 1-3 ug/ml.
Presentation
PBS, pH 7.2, 0.1% sodium azide.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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