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Anti-NEDD8 Antibody (Asp21) LS-C176339

Catalog Size Price
LS-C176339-100 100 µl Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human NEDD8
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated

Details

Human NEDD8
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot

Specificity and Use

NEDD8 antibody was raised against synthetic peptide around Asp21 of human NEDD8
Asp21
Human NEDD8

Packaging

PBS, pH 7.2, 0.05% sodium azide
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only.

About NEDD8

Q15843 NM_006156 NP_006147.1

NEDD8 Antibody, NEDD-8 Antibody, Neddylin Antibody, Ubiquitin-like protein Nedd8 Antibody

Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

Immunohistochemistry

Immunohistochemistry
IHC of NEDD8 (D21) pAb in paraffin-embedded human lung carcinoma tissue.

Western blot

Western blot
Western blot of NEDD8 (D21) pAb in extracts from Jurkat cells.

Requested From: 
Date Requested: 8/17/2017

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