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Anti-NCOA3 / SRC-3 / AIB1 Antibody (aa3-15) LS-C11788

Ordering

Wt. Vol. Conc. Price
100 µg - - $495
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Rabbit Polyclonal (IgG) to Human NCOA3 / SRC-3 / AIB1
Human
Western blot
Unconjugated

Details

Human NCOA3 / SRC-3 / AIB1
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified

Applications

Western blot

Specificity and Use

NCOA3 / SRC-3 / AIB1 antibody was raised against synthetic peptide: GLGENLDPLASDSC, corresponding to amino acids 3-15 of Human AIB 1. Percent identity by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey, Marmoset (92%); Xenopus (85%).
aa3-15
Detects human amplified in breast cancer 1 (AIB1). Species cross-reactivity: Expected to cross-react with Xenopus laevis (92% identity with immunogen) due to sequence homology.
Western Blot. Western Blot: Predicted molecular weight: 155kD. Can be blocked with AIB 1 peptide. Positive control: T47D cell lysate.

Packaging

PBS, 1 mg/ml BSA, 0.05% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About NCOA3 / SRC-3 / AIB1

Q9Y6Q9 NM_006534 NP_006525.2

NCOA3 Antibody, ACTR Antibody, AIB1 Antibody, BHLHe42 Antibody, CAGH16 Antibody, CBP-interacting protein Antibody, CTG26 Antibody, AIB-1 Antibody, P/CIP Antibody, TNRC14 Antibody, TRAM-1 Antibody, Nuclear receptor coactivator 3 Antibody, PCIP Antibody, RAC-3 Antibody, SRC3 Antibody, TNRC16 Antibody, KAT13B Antibody, NCoA-3 Antibody, SRC-3 Antibody

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity.

Requested From: United States
Date Requested: 9/25/2016

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