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Anti-NALP1 / NLRP1 Antibody (aa161-180) LS-C148277

Note: This antibody replaces LS-C9212


Wt. Vol. Conc. Price
- 50 µl - Unavailable

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100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human NALP1 / NLRP1
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation


Human NALP1 / NLRP1
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)


  • IHC - Paraffin (1:1000 - 1:5000)
  • IHC - Frozen
  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation (1:50 - 1:200)

Specificity and Use

NALP1 / NLRP1 antibody was raised against a synthetic peptide corresponding to amino acids 161-180(PSSPDHESPSQESPNAPTST) of human NALP1/NAC/CARD7, GenBank no. NP_127497.1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%); Orangutan, Monkey (95%); Panda, Bovine (85%); Mouse (60%).


Antiserum, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About NALP1 / NLRP1

Q9C000 NM_014922 NP_055737.1

NLRP1 Antibody, CLR17.1 Antibody, CARD7 Antibody, DEFCAP Antibody, DEFCAP-L/S Antibody, NAC Antibody, SLEV1 Antibody, VAMAS1 Antibody, KIAA0926 Antibody, NALP1 Antibody, PP1044 Antibody

NALP1 / NLRP1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells.


Formalin-fixed, paraffin-embedded human tissue sections probed with NALP1 antibody at 1:2000. A, bone marrow. B, brain glioma core from a brain cancer microarray. A1 and B1 are higher magnifications of A and B, respectively. Hematoxylin-Eos in counterstain.


Formalin-fixed, paraffin-embedded normal human tissue sections probed using NLRP1 antibody at 1:2000. A, epidermis. B, esophagus. C, uterine cervix. D, thymus. Hematoxylin-Eosin counterstain. In A-C, NLRP1 expression is associated with differentiation in stratified epithelial of the skin, esophagus, and cervix.

Western blot

Western blot
Western blot of NLRP1 in adult human tissue lysates using NLRP1 antibody at 1:2000. Full-length NLRP1 protein was detected at highest levels in kidney, brain and epidermis. A smaller band was detected in thymus, possibly representing a NLRP1 breakdown product or alternatively spliced form. 293T/NALP1: positive control, 293T cells transiently transfected with full-length NLRP1.

Requested From: 
Date Requested: 3/28/2017

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