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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NALP1 / NLRP1

NLR family, pyrin domain containing 1

NALP1 / NLRP1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Gene Name: NLR family, pyrin domain containing 1
Synonyms: NLRP1, CLR17.1, CARD7, DEFCAP, DEFCAP-L/S, NAC, SLEV1, VAMAS1, KIAA0926, NALP1, PP1044
Target Sequences: NM_014922 NP_055737.1 Q9C000

Filtered by: None
Target
NALP1 / NLRP1 (22)
Reactivity
Human (22)
Mouse (4)
Bovine (4)
Dog (4)
Gibbon (3)
Horse (4)
Monkey (4)
Application
IHC (12)
IHC-Fr (2)
IHC-P (7)
WB (18)
ELISA (7)
ICC (3)
IF (1)
IP (6)
Host
rabbit (19)
mouse (2)
sheep (1)
Isotype
IgG (13)
IgG1 (2)
Clonality
monoclonal mc (2)
polyclonal pc (20)
Clone
Nalypy1-4 (1)
Format
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (16)
Epitope
aa323-372 (4)
aa2-25 (2)
C-Terminus (1)
aa1-323 (1)
aa1058-1077 (1)
aa161-180 (1)
Publications
No (22)
Showing 1-22 of 22 results

IHC-plus™ NALP1 / NLRP1 Antibody LS-B589
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05mg 1mg/ml  $425.00
Anti-NLRP1 / NALP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunocytochemistry of NALP1 in K562 cells with NALP1 antibody at 10 ug/ml.

IHC-plus™ NALP1 / NLRP1 Antibody (aa323-372) LS-B5845
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Mouse, Dog, Bovine, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl 0.5mg/ml  $485.00
Anti-NLRP1 / NALP1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
NLRP1 / NALP1 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

NALP1 / NLRP1 Antibody (aa323-372, HRP) LS-C458633
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Mouse, Dog, Bovine, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100µl 0.65mg/ml  $405.00
Anti-NLRP1 / NALP1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
NLRP1 / NALP1 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

NALP1 / NLRP1 Antibody (aa323-372, Biotin) LS-C458631
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Mouse, Dog, Bovine, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100µl 1mg/ml  $405.00
Anti-NLRP1 / NALP1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
NLRP1 / NALP1 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

NALP1 / NLRP1 Antibody (aa323-372, FITC) LS-C458632
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Mouse, Dog, Bovine, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100µl 1mg/ml  $405.00
Anti-NLRP1 / NALP1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
NLRP1 / NALP1 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

NALP1 / NLRP1 Antibody (clone Nalypy1-4) LS-C53529
Mouse Monoclonal [clone Nalypy1-4] (IgG1) to Human NALP1 / NLRP1
Human
ICC, IHC, IP, WB
Unconjugated
50µg 1mg/ml  $495.00

NALP1 / NLRP1 Antibody LS-C18688
Mouse Monoclonal (IgG1) to Human NALP1 / NLRP1
Human
ICC, IHC, IP, WB
Unconjugated
100µg 1mg/ml  $395.00

NALP1 / NLRP1 Antibody (aa161-180) LS-C148277
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50µl  $335.00
Formalin-fixed, paraffin-embedded normal human tissue sections probed using NLRP1 antibody at 1:2000. A, epidermis. B, esophagus. C, uterine cervix. D, thymus. Hematoxylin-Eosin counterstain. In A-C, NLRP1 expression is associated with differentiation in stratified epithelial of the skin, esophagus, and cervix.
Formalin-fixed, paraffin-embedded human tissue sections probed with NALP1 antibody at 1:2000. A, bone marrow. B, brain glioma core from a brain cancer microarray. A1 and B1 are higher magnifications of A and B, respectively. Hematoxylin-Eos in counterstain.

NALP1 / NLRP1 Antibody (aa1058-1077) LS-C148276
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50µl  $335.00
Formalin-fixed, paraffin-embedded normal human bone marrow stained for NALP1 (CARD7/NAP) using NALP1 antibody at 1:2000. Hematoxylin-Eosin counterstain. Staining is seen in differentiated granulocytes.

NALP1 / NLRP1 Antibody LS-C751780
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA, IHC, WB
Unconjugated
100µg  $375.00

NALP1 / NLRP1 Antibody LS-C358720
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
IHC, IP, WB
Unconjugated
50µl  $325.00

NALP1 / NLRP1 Antibody LS-C358697
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
IHC, IP, WB
Unconjugated
50µl  $325.00

NALP1 / NLRP1 Antibody LS-C809017
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00

NALP1 / NLRP1 Antibody (aa2-25) LS-C9208
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
WB
Unconjugated
100µl  $680.00

NALP1 / NLRP1 Antibody LS-C18602
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
WB
Unconjugated
100µl  $425.00

NALP1 / NLRP1 Antibody (C-Terminus) LS-C9210
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
WB
Unconjugated
100µg  $530.00

NALP1 / NLRP1 Antibody LS-C398454
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunofluorescence staining of SH-SY5Y cells with NLRP1 Antibody at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

NALP1 / NLRP1 Antibody (HRP) LS-C398455
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

NALP1 / NLRP1 Antibody (Biotin) LS-C398419
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

NALP1 / NLRP1 Antibody (FITC) LS-C398421
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00

NALP1 / NLRP1 Antibody (aa2-25) LS-C345053
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
WB
Unconjugated
100µg  $375.00
Western blot analysis of human and mouse cell lines using anti-human NLRP1/NALP1 antibody (AL176) .Method: Total protein extracts (20 ug) from various human (293-T, Jurkat, Raji, Ramos, BJAB, THP-1, U937, K562, Raw, HeLa) and mouse (EL-4, A20) cell lines were run on SDS-PAGE and NLRP1/NALP1 detected using anti-human NLRP1/NALP1 antibody (AL176) at 1:500 dilution. Anti-rabbit IgG coupled horse radish peroxidase was used at 1:5000 dilution for ECL detection.

NALP1 / NLRP1 Antibody (aa1-323) LS-C184850
Sheep Polyclonal (IgG) to Human NALP1 / NLRP1
Human
WB
Unconjugated
100µg  $770.00
Showing 1-22 of 22 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).