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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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NALP1 / NLRP1

NLR family, pyrin domain containing 1

NALP1 / NLRP1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Gene Name: NLR family, pyrin domain containing 1
Synonyms: NLRP1, CLR17.1, CARD7, DEFCAP, DEFCAP-L/S, NAC, SLEV1, VAMAS1, KIAA0926, NALP1, PP1044
Target Sequences: NM_014922 NP_055737.1 Q9C000


☰ Filters
Product Group
IgG (13)
IgG1 (2)
No (21)
NALP1 / NLRP1 Antibody - Anti-NLRP1 / NALP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
NALP1 / NLRP1 Antibody - Anti-NLRP1 / NALP1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Mouse, Dog, Bovine, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $485.00
NALP1 / NLRP1 Antibody - Anti-NLRP1 / NALP1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Mouse, Dog, Bovine, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100µl   0.65mg/ml   $405.00
NALP1 / NLRP1 Antibody - Anti-NLRP1 / NALP1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Mouse, Dog, Bovine, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100µl   1mg/ml   $405.00
NALP1 / NLRP1 Antibody - Anti-NLRP1 / NALP1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Mouse, Dog, Bovine, Horse, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100µl   1mg/ml   $405.00
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Mouse Monoclonal [clone Nalypy1-4] (IgG1) to Human NALP1 / NLRP1
Human
ICC, IHC, IP, WB
Unconjugated
50µg   1mg/ml   $495.00
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Mouse Monoclonal (IgG1) to Human NALP1 / NLRP1
Human
ICC, IHC, IP, WB
Unconjugated
100µg   1mg/ml   $405.00
NALP1 / NLRP1 Antibody - Formalin-fixed, paraffin-embedded normal human tissue sections probed using NLRP1 antibody at 1:2000. A, epidermis. B, esophagus. C, uterine cervix. D, thymus. Hematoxylin-Eosin counterstain. In A-C, NLRP1 expression is associated with differentiation in stratified epithelial of the skin, esophagus, and cervix.
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Rabbit Polyclonal to Human NALP1 / NLRP1
Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50µl   $335.00
NALP1 / NLRP1 Antibody - Formalin-fixed, paraffin-embedded normal human bone marrow stained for NALP1 (CARD7/NAP) using NALP1 antibody at 1:2000. Hematoxylin-Eosin counterstain. Staining is seen in differentiated granulocytes.
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Rabbit Polyclonal to Human NALP1 / NLRP1
Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50µl   $335.00
Select
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA, IHC, WB
Unconjugated
100µg   $375.00
Select
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
IHC, IP, WB
Unconjugated
50µl   $325.00
Select
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
IHC, IP, WB
Unconjugated
50µl   $325.00
Select
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
WB
Unconjugated
100µl   $680.00
Select
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
WB
Unconjugated
100µg   $530.00
NALP1 / NLRP1 Antibody - Immunofluorescence staining of SH-SY5Y cells with NLRP1 Antibody at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA
HRP Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human
ELISA
FITC Conjugated
50µg   $285.00; 100µg   $385.00
NALP1 / NLRP1 Antibody - Western blot analysis of human and mouse cell lines using anti-human NLRP1/NALP1 antibody (AL176) .Method: Total protein extracts (20 ug) from various human (293-T, Jurkat, Raji, Ramos, BJAB, THP-1, U937, K562, Raw, HeLa) and mouse (EL-4, A20) cell lines were run on SDS-PAGE and NLRP1/NALP1 detected using anti-human NLRP1/NALP1 antibody (AL176) at 1:500 dilution. Anti-rabbit IgG coupled horse radish peroxidase was used at 1:5000 dilution for ECL detection.
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Rabbit Polyclonal to Human NALP1 / NLRP1
Human
WB
Unconjugated
100µg   $375.00
Select
Sheep Polyclonal (IgG) to Human NALP1 / NLRP1
Human
WB
Unconjugated
100µg   $770.00
Viewing 1-21 of 21 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).