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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MUSK Antibody (clone 2H6) LS‑C133332
MUSK antibody LS-C133332 is an unconjugated mouse monoclonal antibody to human MUSK. Validated for ELISA, IHC and WB.
Catalog
Size
Price
LS-C133332-100
100 µg (1 mg/ml)
Unavailable

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Applications: Western blot, ELISA
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
MUSK antibody LS-C146062 Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Guinea pig, Rabbit
Applications: Western blot

Product Description

MUSK antibody LS-C133332 is an unconjugated mouse monoclonal antibody to human MUSK. Validated for ELISA, IHC and WB.
About MUSK
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. O15146 NM_005592 NP_005583.1

MUSK Antibody, Nsk1 Antibody, Nsk2 Antibody, MDK4 Antibody, Muscle-specific MUSK receptor Antibody


Specifications

Target
Human MUSK
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal [2H6]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1 µg/ml)
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MUSK antibody was raised against mUSK (NP_005583, 301 a.a. ~ 400 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human MUSK
Usage
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot: Cell lysate, Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MUSK on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1 ug/ml]
Immunoperoxidase of monoclonal antibody to MUSK on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1 ug/ml]

Western blot

MUSK monoclonal antibody (M07), clone 2H6 Western blot of MUSK expression in Jurkat.
MUSK monoclonal antibody (M07), clone 2H6 Western blot of MUSK expression in Jurkat.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MUSK is 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MUSK is 1 ng/ml as a capture antibody.

Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MUSK on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1 ug/ml]
Immunoperoxidase of monoclonal antibody to MUSK on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1 ug/ml]

Western blot

MUSK monoclonal antibody (M07), clone 2H6 Western blot of MUSK expression in Jurkat.
MUSK monoclonal antibody (M07), clone 2H6 Western blot of MUSK expression in Jurkat.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MUSK is 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MUSK is 1 ng/ml as a capture antibody.

Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MUSK on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1 ug/ml]
Immunoperoxidase of monoclonal antibody to MUSK on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1 ug/ml]

Western blot

MUSK monoclonal antibody (M07), clone 2H6 Western blot of MUSK expression in Jurkat.
MUSK monoclonal antibody (M07), clone 2H6 Western blot of MUSK expression in Jurkat.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MUSK is 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MUSK is 1 ng/ml as a capture antibody.

Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MUSK on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1 ug/ml]
Immunoperoxidase of monoclonal antibody to MUSK on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1 ug/ml]

Western blot

MUSK monoclonal antibody (M07), clone 2H6 Western blot of MUSK expression in Jurkat.
MUSK monoclonal antibody (M07), clone 2H6 Western blot of MUSK expression in Jurkat.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MUSK is 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MUSK is 1 ng/ml as a capture antibody.


Requested From: 
Date Requested: 6/20/2018

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