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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MTOR Antibody (Ser2481) LS‑C16625
MTOR antibody LS-C16625 is an unconjugated rabbit polyclonal antibody to MTOR from human, mouse, rat and other species. Validated for ELISA, IP and WB.
Antibody
Catalog
Size
Price
LS-C16625-100
100 µl
$530

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Product Description

MTOR antibody LS-C16625 is an unconjugated rabbit polyclonal antibody to MTOR from human, mouse, rat and other species. Validated for ELISA, IP and WB.
About MTOR
Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). P42345 NM_004958 NP_004949.1

MTOR Antibody, FRAP1 Antibody, FRAP2 Antibody, FRAP Antibody, Mammalian target of rapamycin Antibody, RAFT1 Antibody, Rapamycin and FKBP12 target 1 Antibody, RAPT1 Antibody, Rapamycin target protein 1 Antibody


Specifications

Target
Human MTOR
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • Immunoprecipitation (1:100)
  • ELISA
Immunogen
MTOR antibody was raised against synthetic peptide (KLH coupled) corresponding to residues surrounding Ser2481 of human mTOR.
Epitope
Ser2481
Specificity
Detects endogenous levels of total human mTOR. It cross-reacts weakly with some other proteins based on Western analysis. Species cross-reactivity: Mouse, monkey and rat.
Usage
Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:1000, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4?C with gentle shaking, overnight. Immunoprecipitation: 1:100.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 50% Glycerol, No preservatives added
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/17/2018

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