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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MTNR1B / MT2 Antibody (N‑Terminus) LS‑C151615
MT2 antibody LS-C151615 is an unconjugated rabbit polyclonal antibody to human MT2 (MTNR1B). Validated for WB.
Catalog
Size
Price
LS-C151615-50
50 µg (1 mg/ml)
Unavailable

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Product Description

MT2 antibody LS-C151615 is an unconjugated rabbit polyclonal antibody to human MT2 (MTNR1B). Validated for WB.
About MTNR1B / MT2
MTNR1B / MT2 is one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. P49286 NM_005959 NP_005950.1

MTNR1B Antibody, MEL-1B-R Antibody, Mel-1b melatonin receptor Antibody, Melatonin receptor 1B Antibody, Melatonin receptor MEL1B Antibody, Mt2r Antibody, MT2 melatonin receptor Antibody, MtT2 receptor Antibody, Melatonin receptor type 1B Antibody, MT2 Antibody, FGQTL2 Antibody, Mel1b receptor Antibody


Specifications

Target
Human MTNR1B / MT2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
MTNR1B / MT2 antibody was raised against synthetic peptide from N-Terminus of human MTNR1B (P49286, NP_005950). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%).
Blocking Peptide
LS-E23367 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C151615. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human MTNR1B
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

MTNR1B / MT2 antibody Western Blot of HepG2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
MTNR1B / MT2 antibody Western Blot of HepG2. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

MTNR1B / MT2 antibody Western Blot of HepG2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
MTNR1B / MT2 antibody Western Blot of HepG2. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

MTNR1B / MT2 antibody Western Blot of HepG2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
MTNR1B / MT2 antibody Western Blot of HepG2. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

MTNR1B / MT2 antibody Western Blot of HepG2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
MTNR1B / MT2 antibody Western Blot of HepG2. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/19/2018

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