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Catalog Number Size Price
LS-A932-50 50 µg (1 mg/ml) $460 
MTNR1B / MT2 Antibody - Anti-MTNR1B / MT2 antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MTNR1B / MT2 Antibody - Eye, Retina
MTNR1B / MT2 Antibody - Brain, Glioblastoma
MTNR1B / MT2 Antibody - Anti-MTNR1B antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MTNR1B / MT2 Antibody - Anti-MTNR1B / MT2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MTNR1B / MT2 Antibody - Anti-MTNR1B / MT2 antibody IHC of human eye. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MTNR1B / MT2 Antibody - Anti-MTNR1B / MT2 antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MTNR1B / MT2 Antibody - Eye, Retina
MTNR1B / MT2 Antibody - Brain, Glioblastoma
MTNR1B / MT2 Antibody - Anti-MTNR1B antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MTNR1B / MT2 Antibody - Anti-MTNR1B / MT2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
MTNR1B / MT2 Antibody - Anti-MTNR1B / MT2 antibody IHC of human eye. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human MTNR1B / MT2 Antibody (Cytoplasmic Domain, IHC) LS‑A932

PathPlus™ Polyclonal Rabbit anti‑Human MTNR1B / MT2 Antibody (Cytoplasmic Domain, IHC) LS‑A932

Antibody:
MTNR1B / MT2 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-A932-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
MTNR1B / MT2 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Melatonin receptor 1B (MTNR1B) is one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. MTNR1B is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human MTNR1B / MT2
Synonyms
MTNR1B | MEL-1B-R | Mel-1b melatonin receptor | Melatonin receptor 1B | Melatonin receptor MEL1B | Mt2r | MT2 melatonin receptor | MtT2 receptor | Melatonin receptor type 1B | MT2 | FGQTL2 | Mel1b receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human MTNR1B. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (94%); Bat (88%).
Epitope
Cytoplasmic Domain
Specificity
Human MTNR1B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (8 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MTNR1B / MT2
P49286 NM_005959 NP_005950.1

Validation

MTNR1B / MT2 Antibody - Anti-MTNR1B / MT2 antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B / MT2 antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B / MT2 antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MTNR1B / MT2 Antibody - Eye, Retina
Eye, Retina
Eye, Retina

MTNR1B / MT2 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

MTNR1B / MT2 Antibody - Anti-MTNR1B antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MTNR1B / MT2 Antibody - Anti-MTNR1B / MT2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B / MT2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B / MT2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MTNR1B / MT2 Antibody - Anti-MTNR1B / MT2 antibody IHC of human eye. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B / MT2 antibody IHC of human eye. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B / MT2 antibody IHC of human eye. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ MTNR1B / MT2 Antibody (Cytoplasmic Domain) for IHC LS-A932 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/16/2021