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Anti-MRE11A / MRE11 Antibody (aa182-582, clone 12D7) IHC-plus™ LS-B1700

Note: This antibody replaces LS-C20019

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MRE11A / MRE11 Antibodies

Anti-MRE11A / MRE11 Antibody (aa68-706) IHC-plus™ LS-B1447
Rabbit Polyclonal to Mouse MRE11A / MRE11
Mouse, Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MRE11A / MRE11 Antibody (aa182-582, clone 4H9) LS-C53370
Mouse Monoclonal [clone 4H9] (IgG1) to Human MRE11A / MRE11
Human
IHC, Western blot
Unconjugated
Anti-MRE11A / MRE11 Antibody LS-C155765
Rabbit Polyclonal (IgG) to Yeast MRE11A / MRE11
Yeast
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 12D7] (IgG1) to Human MRE11A / MRE11
Human
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human MRE11A / MRE11
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [12D7]
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence
  • Western blot
  • Immunoprecipitation
  • ELISA

Specificity and Use

MRE11A / MRE11 antibody was raised against recombinant human MRE11A / MRE11.
aa182-582
Amino acids 182-582 of Mre11 expressed in E. coli.
Immunohistochemistry: LS-B1700 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1700 was determined to be 5 ug/ml.

Packaging

PBS, pH 7.4. No preservative added.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About MRE11A / MRE11

P49959 NM_005591 NP_005582.1

MRE11A Antibody, AT-like disease Antibody, Endo/exonuclease Mre11 Antibody, HNGS1 Antibody, MRE11 Antibody, MRE11 homolog 1 Antibody, MRE11 homolog A Antibody, MRE11B Antibody, ATLD Antibody

Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity.

Immunohistochemistry

Immunohistochemistry
Anti-MRE11A / MRE11 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1700 concentration 5 ug/ml.
 

Requested From: United States
Date Requested: 12/9/2016

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