Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone LT10] (IgG1) to Human MME / CD10
Human MME / CD10
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [LT10]
Ion exchange chromatography
Specificity and Use
MME / CD10 antibody was raised against mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation).
Reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kD type II integral membrane protein.
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 15 mM sodium azide, 0.2% high-grade protease free BSA as a stabilizing agent.
MME / CD10 is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues.