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Anti-MIB1 Antibody (aa13-42) LS-C99610

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MIB1 Antibodies

Anti-MIB1 Antibody (HRP) LS-C211424
Rabbit Polyclonal (IgG) to Human MIB1
Human
Western blot, ELISA
HRP Conjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human MIB1
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated

Details

Human MIB1
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Immunofluorescence (1:20 - 1:100)
  • Western blot (1:1000)

Specificity and Use

MIB1 antibody was raised against kLH-conjugated synthetic peptide between amino acids 13-42 from N-terminal region of human Mib1/Mindbomb.
LS-E6914 - Lyophilized - 100 µg - $145.00
aa13-42

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About MIB1

Q86YT6 AB037744 BAA92561.1

MIB1 Antibody, DIP-1 Antibody, DIP1 Antibody, Mindbomb homolog 1 Antibody, KIAA1323 Antibody, Mind bomb homolog 1 Antibody, Ubiquitin ligase protein MIB1 Antibody, Ubiquitin ligase mind bomb Antibody, ZZZ6 Antibody, DAPK-interacting protein 1 Antibody, Mib Antibody, ZZANK2 Antibody

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis By similarity.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Immunofluorescence

Immunofluorescence
Immunofluorescent staining of HeLa cells incubated with MIB Antibody at a dilution of 1:20. Data courtesy of Dr. Vyacheslav Akimov, University of Southern Denmark.

Western blot

Western blot
MIB Antibody (K28) western blot of K562 cell line lysates (35 ug/lane). The MIB antibody detected the MIB protein (arrow).
 

Requested From: United States
Date Requested: 12/6/2016

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