Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone RDR34] (IgG2b) to Rabbit MHC Class II RLA-DR
IHC, Immunoprecipitation, Flow Cytometry
Mouse Monoclonal (IgG2b,k) to Rabbit MHC Class II RLA-DR
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Rabbit MHC Class II RLA-DR
Rabbit (tested or 100% immunogen sequence identity)
IHC - Frozen
Specificity and Use
Rabbit leukemic B-cell line.
Recognizes rabbit RLA-DR chain (Mr ~35kD). Reacts with RLA-DR-transfected cells, but not with RLA-DQ-transfected cells and, in normal adult rabbits, 50-60% of peripheral blood leukocytes and splenocytes. It has been reported that the antibody stains: lymphocytes in the thymic medulla and some cells in the cortex; periportal cells in the liver; and synovial lining cell (i. e., infiltrating macrophages) in inflamed synovium.
Flow cytometry. Immunohistochemistry (acetone-fixed, frozen tissue sections). Immunoprecipitation. Flow Cytometry: 1 ug/1E6 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 0.1% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Sensitive to light.