Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone TDR31.1] (IgG1) to Human MHC Class II
IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry
Mouse Monoclonal [clone PF8J-9B] (IgG2a) to Cat MHC Class II
Western blot, Flow Cytometry, ELISA
Cat MHC Class II
Cat (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [PF8J-9B]
Protein A purified
Specificity and Use
PBS, 0.05% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.
About MHC Class II
MHC (major histocompatibility complex) class II molecules are a family of molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells. The antigens presented by class II peptides are derived from extracellular proteins (not cytosolic as in class I); hence, the MHC class II-dependent pathway of antigen presentation is called the endocytic or exogenous pathway.