Mouse MHC Class II

Rat

Mouse (tested or 100% immunogen sequence identity)

IgG2b Monoclonal

ER-TR2

Unconjugated

Affinity purified

Unmodified

Murine thymic reticulum

MHC Class II antigens are heterodimers consisting of one a- chain (31-34kDa) and one beta-chain (26-29kDa). The epitope has not been further characterized. Antigen distribution Isolated cells: The antigen is found on dendritic cells, B-cells and macrophages. The level of antigen detected by ER-TR1, ER-TR2 and ER-TR3 differs from strain to strain (see table below). Tissue Sections: The antigen is found on B-cells, interdigitating cells and macrophages in peripheral lymphoid organs but is absent from T-cells. It is also expressed as a fine reticular pattern on stromal thymic cells of the cortex and as a confluent pattern on stromal thymic cells of the medulla. Specificity: Mouse: cells expressing MHC class II antigens Other species: negative on human, others not tested.

• IHC
• IHC - Frozen (1:200)

Lyophilized from PBS, pH 7.2, 5 mg/ml BSA, 0.05% Kathon

Reconstitute with 0.5ml distilled H2O.

Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles. Store undiluted.

For research use only. Intended for use by laboratory professionals.

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