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Anti-MDM2 Antibody (aa179-193) LS-C55101

Note: This antibody replaces LS-C72326

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MDM2 Antibodies

Anti-MDM2 Antibody (aa154-167, clone SMP14) IHC-plus™ LS-B163
Mouse Monoclonal [clone SMP14] (IgG1) to Human MDM2
Human, Monkey, Rat, Dog
IHC - Paraffin, IHC - Frozen, IHC - Resin, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-MDM2 Antibody (clone 1A7) IHC-plus™ LS-B5461
Mouse Monoclonal [clone 1A7] (IgG1,k) to Human MDM2
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MDM2 Antibody (Internal) LS-C209837
Rabbit Polyclonal (IgG) to Zebrafish MDM2
Zebrafish
IHC, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human MDM2
Human, Monkey
Western blot, ELISA
Unconjugated

Details

Human MDM2
Goat
Human, Monkey (tested or 100% immunogen sequence identity)
Bat, Bovine, Horse, Pig (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1:64000) & (0.3 - 1 µg/ml)
  • ELISA (1:64000)

Specificity and Use

MDM2 antibody was raised against synthetic peptide C-DELSGERQRKRHKSD from an internal region of human MDM2 (NP_002383.2). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%); Panda, Bovine, Cat, Bat, Horse, Pig (93%); Dog, Opossum, Platypus (87%); Rat, Zebrafish (80%).
LS-E25981 - Lyophilized - 100 µg - $145.00
aa179-193
Human MDM2. This antibody is expected to recognize isoform MDM2 (NP_002383.2) only.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About MDM2

Q00987 NM_002392 NP_002383.2

MDM2 Antibody, ACTFS Antibody, Double minute 2 protein Antibody, Hdm2 Antibody, MDM2 variant FB30 Antibody, HDMX Antibody, Oncoprotein Mdm2 Antibody, p53-binding protein Mdm2 Antibody, MDM2 variant FB28 Antibody

E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein.

Western blot

Western blot
Antibody (0.3 ug/ml) staining of Human Liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
 

Requested From: United States
Date Requested: 12/7/2016

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