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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MCF2L / DBS Antibody (aa1049‑1075) IHC‑plus™ LS‑B9783
Note: This antibody replaces LS-C158113
DBS antibody LS-B9783 is an unconjugated rabbit polyclonal antibody to human DBS (MCF2L). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B9783-200
200 µl
Unavailable

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Product Description

DBS antibody LS-B9783 is an unconjugated rabbit polyclonal antibody to human DBS (MCF2L). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
About MCF2L / DBS
Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus By similarity. Isoform 5 activates CDC42. O15068 NM_024979 NP_079255.4

MCF2L Antibody, ARHGEF14 Antibody, DBS Antibody, KIAA0362 Antibody, OST Antibody, DBLs big sister Antibody


Specifications

Target
Human MCF2L / DBS
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E6163 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B9783. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa1049-1075
Specificity
This MCF2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1049-1075 amino acids from the C-terminal region of human MCF2L.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-MCF2L / DBS antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9783 dilution 1:100.
Anti-MCF2L / DBS antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9783 dilution 1:100.

Western blot

MCF2L Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The MCF2L antibody detected the MCF2L protein (arrow).
MCF2L Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The MCF2L antibody detected the MCF2L protein (arrow).

Immunohistochemistry

Anti-MCF2L / DBS antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9783 dilution 1:100.
Anti-MCF2L / DBS antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9783 dilution 1:100.

Western blot

MCF2L Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The MCF2L antibody detected the MCF2L protein (arrow).
MCF2L Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The MCF2L antibody detected the MCF2L protein (arrow).

Immunohistochemistry

Anti-MCF2L / DBS antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9783 dilution 1:100.
Anti-MCF2L / DBS antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9783 dilution 1:100.

Western blot

MCF2L Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The MCF2L antibody detected the MCF2L protein (arrow).
MCF2L Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The MCF2L antibody detected the MCF2L protein (arrow).

Immunohistochemistry

Anti-MCF2L / DBS antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9783 dilution 1:100.
Anti-MCF2L / DBS antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9783 dilution 1:100.

Western blot

MCF2L Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The MCF2L antibody detected the MCF2L protein (arrow).
MCF2L Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The MCF2L antibody detected the MCF2L protein (arrow).


Requested From: 
Date Requested: 6/23/2018

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