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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MC1R Antibody (3rd Cytoplasmic Domain) LS‑C16499
Antibody
MC1R antibody LS-C16499 is an unconjugated rabbit polyclonal antibody to mouse MC1R. Validated for ELISA and WB.
Catalog
Size
Price
LS-C16499-50
50 µg
Unavailable

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Product Description

MC1R antibody LS-C16499 is an unconjugated rabbit polyclonal antibody to mouse MC1R. Validated for ELISA and WB.
About MC1R
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Q01726 NM_002386 NP_002377.4

MC1R Antibody, CMM5 Antibody, MC1 receptor Antibody, MC1-R Antibody, MSHR Antibody, Melanocortin receptor 1 Antibody, Melanotropin receptor Antibody, Melanocortin 1 receptor Antibody, MSH-R Antibody, SHEP2 Antibody


Specifications

Target
Mouse MC1R
Host
Rabbit
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 10 µg/ml)
  • ELISA (1:10000 - 1:100000)
Immunogen
MC1R antibody was raised against a 21 mer peptide (designated MCR11) from the 3rd cytoplasmic domain of mouse MC1-R.
Epitope
3rd Cytoplasmic Domain
Specificity
Recognizes mouse Melanocyte Stimulating Hormone Receptor (MSH-R). Species cross-reactivity: Mouse. Species sequence homology: human-70%, bovine sheep, equine-66% and canine-60%.
Usage
Suitable for use in ELISA and Western Blot. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide per well. Western Blot: 1-10 ug/ml using Chemiluminescence.
Presentation
PBS, pH 7.4, 0.1% BSA, 0.02% sodium azide.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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