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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MBP / Myelin Basic Protein Antibody IHC‑plus™ LS‑B3112
Note: This antibody replaces LS-C25703
Myelin Basic Protein antibody LS-B3112 is an unconjugated rabbit polyclonal antibody to human Myelin Basic Protein (MBP). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B3112-50
50 µl
Unavailable

Popular MBP / Myelin Basic Protein Products

Anti-Myelin Basic Protein antibody IHC of human brain, oligodendrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2231 concentration 5 ug/ml.
Species: Human, Mouse, Rat, Goat, Rabbit, Sheep, Primate
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3315 concentration 10 ug/ml.
Species: Human, Bovine, Guinea pig, Rabbit, Sheep
Applications: IHC, IHC - Paraffin, ELISA, Radioimmunoassay
Anti-Myelin Basic Protein antibody IHC of human brain cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6794 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin
Anti-Myelin Basic Protein / MBP antibody IHC of human brain, cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8056 dilution 1:100.
Species: Rat
Applications: IHC, IHC - Paraffin
Myelin Basic Protein / MBP antibody. IHC(P): Rat Brain Tissue.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Sheep
Applications: IHC, IHC - Paraffin, Western blot

Product Description

Myelin Basic Protein antibody LS-B3112 is an unconjugated rabbit polyclonal antibody to human Myelin Basic Protein (MBP). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
About MBP / Myelin Basic Protein
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. P02686 NM_002385 NP_002376.1

MBP Antibody, Myelin A1 protein Antibody, Myelin basic protein Antibody


Specifications

Target
Human MBP / Myelin Basic Protein
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:1500)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Human myelin basic protein from brain.
Specificity
Suitable for labeling of oligodendrocytes and myelin of white matter in brain and spinal cord (gray matter stains less abundantly). Also stains peripheral nerves.
Usage
Immunohistochemistry: LS-B3112 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3112 was determined to be 1:100. Western Blot: 1:1500 in TTBS, overnight at 4uC.
Presentation
0.05M Tris HCL, pH 7.6, 15 mM sodium azide before the addition of glycerol to 40%
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.

Immunohistochemistry

Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.

Immunohistochemistry

Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.

Immunohistochemistry

Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.

Immunohistochemistry

Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.

Immunohistochemistry

Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.

Immunohistochemistry

Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.

Immunohistochemistry

Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3112 dilution 1:100.


Requested From: 
Date Requested: 6/20/2018

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