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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MBP / Myelin Basic Protein

myelin basic protein

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

Gene Name: myelin basic protein
Synonyms: MBP, Myelin A1 protein, Myelin basic protein
Target Sequences: NM_002385 NP_002376.1 P02686

Filtered By: None
Target
MBP / Myelin Basic Protein (150)
Reactivity
Human (125)
Mouse (48)
Rat (71)
All species (1)
Bat (5)
Bovine (26)
Chicken (2)
Chimpanzee (6)
Cynomolgus monkey (4)
Dog (9)
Gibbon (6)
Goat (1)
Guinea pig (15)
Hamster (1)
Horse (9)
Mammal (2)
Monkey (6)
Orangutan (6)
Pig (44)
Primate (1)
Rabbit (16)
Sheep (10)
Application
IHC (78)
IHC-Fr (16)
IHC-P (19)
WB (110)
Flo (1)
DB (8)
ELISA (55)
Func (4)
ICC (11)
IF (8)
IP (1)
RIA (7)
Host
rabbit (85)
mouse (56)
goat (2)
chicken (5)
rat (2)
Isotype
IgG (69)
IgG1 (13)
IgG1,k (9)
IgG2a (17)
IgG2b (6)
IgG2b,k (8)
IgM (1)
IgY (3)
Clonality
monoclonal mc (58)
polyclonal pc (92)
Clone
12 (1)
2 (1)
2H9 (1)
5F12-B10 (1)
7D2 (1)
7G7 (1)
ABT-MBP (1)
BM15 (2)
C3 (8)
P12 (1)
QD-9 (1)
V/h5 (1)
Format
AP Conjugated (4)
APC (5)
APC Conjugated (7)
Biotin Conjugated (14)
Cy3 Conjugated (5)
Cy7 Conjugated (5)
FITC Conjugated (15)
HRP Conjugated (15)
PE Conjugated (9)
Ready-to-Use (2)
Unconjugated (76)
Epitope
aa18-222 (10)
pThr98 (10)
aa220-301 (9)
Tyr203 (8)
aa135-190 (8)
pTyr203 (8)
aa107-156 (4)
aa179-228 (4)
aa129-138 (2)
aa182-197 (2)
aa67-74 (2)
aa82-91 (2)
C-Terminus (1)
Internal (1)
N-Terminus (1)
Thr98 (1)
aa119-131 (1)
aa130-136 (1)
aa147-158 (1)
aa215-221 (1)
aa264-277 (1)
aa291-295 (1)
aa36-50 (1)
aa49-62 (1)
aa68-86 (1)
aa69-86 (1)
aa82-87 (1)
aa84-89 (1)
Publications
No (150)
Showing 1-25 of 150 results

MBP / Myelin Basic Protein Antibody (clone 7D2) IHC-plus™ LS-B8056
Mouse Monoclonal [clone 7D2] (IgG1) to Rat MBP / Myelin Basic Protein
Rat
ICC IHC IHC-P WB
Unconjugated
100µl  $425.00
Anti-Myelin Basic Protein / MBP antibody IHC of human brain, cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Rat mixed neuron/glial cultures stained with Myelin Basic Protein antibody (red), and also with chicken antibody to neurofilament NF-L CPCA-NF-L (green). Blue is a DNA stain. Note that the MBP antibody stains an oligodendrocyte and some membrane shed from this cell. Other cells in the field include neurons, astrocytes, microglia and fibroblasts, all of which are completely negative for MBP, though the neuronal processes can be seen with the NF-L antibody.
Anti-Myelin Basic Protein / MBP antibody IHC of human brain, cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Rat mixed neuron/glial cultures stained with Myelin Basic Protein antibody (red), and also with chicken antibody to neurofilament NF-L CPCA-NF-L (green). Blue is a DNA stain. Note that the MBP antibody stains an oligodendrocyte and some membrane shed from this cell. Other cells in the field include neurons, astrocytes, microglia and fibroblasts, all of which are completely negative for MBP, though the neuronal processes can be seen with the NF-L antibody.

MBP / Myelin Basic Protein Antibody (aa130-136) IHC-plus™ LS-B2231
Mouse Monoclonal (IgG2b) to Human MBP / Myelin Basic Protein
Rabbit, Mouse, Goat, Sheep, Rat, Primate, Human
ELISA IHC IHC-Fr IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-Myelin Basic Protein antibody IHC of human brain, oligodendrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-Myelin Basic Protein antibody IHC of human brain, oligodendrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

MBP / Myelin Basic Protein Antibody (N-Terminus, clone V/h5) IHC-plus™ LS-B3315
Mouse Monoclonal [clone V/h5] (IgG1) to Human MBP / Myelin Basic Protein
Rabbit, Guinea pig, Sheep, Bovine, Human
ELISA IHC IHC-P RIA
Unconjugated
50µg 1mg/ml  $425.00
Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

MBP / Myelin Basic Protein Antibody (aa49-62) IHC-plus™ LS-B6794
Rabbit Polyclonal to Human MBP / Myelin Basic Protein
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µg 1mg/ml  $425.00
Anti-Myelin Basic Protein antibody IHC of human brain cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Myelin Basic Protein Antibody - Western blot of Myelin Basic Protein (MBP) with MBP antibody at 1:500 dilution. Detects 22 kD isoform in 10 ug of normal brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-Myelin Basic Protein antibody IHC of human brain cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Myelin Basic Protein Antibody - Western blot of Myelin Basic Protein (MBP) with MBP antibody at 1:500 dilution. Detects 22 kD isoform in 10 ug of normal brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MBP / Myelin Basic Protein Antibody (aa82-87, clone 12) IHC-plus™ LS-B4814
Rat Monoclonal [clone 12] (IgG2a) to Bovine MBP / Myelin Basic Protein
Chicken, Sheep, Bovine, Rabbit, Mouse, Guinea pig, Rat, Pig, Mammal, Human
ELISA IHC IHC-P RIA WB
Unconjugated
125µl  $425.00
Anti-Myelin Basic Protein antibody IHC of human myelin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-Myelin Basic Protein antibody IHC of human myelin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

MBP / Myelin Basic Protein Antibody (aa182-197) LS-C312288
Rabbit Polyclonal to Human MBP / Myelin Basic Protein
Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $355.00
Myelin Basic Protein / MBP antibody. IHC(P): Rat Brain Tissue.
WB of Myelin Basic Protein / MBP antibody. All lanes: Anti-MBP at 0.5ug/ml. WB: Mouse Brain Tissue Lysate at 40ug. Predicted bind size: 33KD. Observed bind size: 33KD.
Myelin Basic Protein / MBP antibody. IHC(P): Rat Brain Tissue.
WB of Myelin Basic Protein / MBP antibody. All lanes: Anti-MBP at 0.5ug/ml. WB: Mouse Brain Tissue Lysate at 40ug. Predicted bind size: 33KD. Observed bind size: 33KD.

MBP / Myelin Basic Protein Antibody IHC-plus™ LS-B8641
Rabbit Polyclonal (IgG) to Human MBP / Myelin Basic Protein
Human
IHC IHC-P
Unconjugated
250µl  $485.00
Anti-Myelin Basic Protein / MBP antibody IHC of human brain cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-Myelin Basic Protein / MBP antibody IHC of human brain cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

MBP / Myelin Basic Protein Antibody LS-C130898
Rabbit Polyclonal (IgG) to Human MBP / Myelin Basic Protein
Rat, Human
ELISA WB
Unconjugated
1000µl 1mg/ml  $485.00

MBP / Myelin Basic Protein Antibody IHC-plus™ LS-B10012
Chicken Polyclonal (IgY) to Human MBP / Myelin Basic Protein
Mouse, Human
ICC IHC IHC-P WB
Unconjugated
100µl 0.1mg/ml  $425.00
Anti-Myelin Basic Protein / MBP antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
Anti-Myelin Basic Protein / MBP antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.

MBP / Myelin Basic Protein Antibody (phospho-Thr98) LS-C43772
Mouse Monoclonal (IgG2a) to Human MBP / Myelin Basic Protein
Human
ELISA IHC IHC-Fr WB
Unconjugated
100µg 1mg/ml  $405.00

MBP / Myelin Basic Protein Antibody (aa129-138) LS-C25713
Mouse Monoclonal (IgG2a) to Bovine MBP / Myelin Basic Protein
Rabbit, Bovine, Rat, Human
ELISA IHC IHC-Fr WB
Unconjugated
2000µl  $605.00

MBP / Myelin Basic Protein Antibody IHC-plus™ LS-B3112
Rabbit Polyclonal (IgG) to Human MBP / Myelin Basic Protein
Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-Myelin Basic Protein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

MBP / Myelin Basic Protein Antibody (C-Terminus) LS-C122173
Rabbit Polyclonal (IgG) to Human MBP / Myelin Basic Protein
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µg  $530.00

MBP / Myelin Basic Protein Antibody (clone 2H9) LS-C355353
Mouse Monoclonal [clone 2H9] (IgG1) to Human MBP / Myelin Basic Protein
Human
Flo ICC IF IHC WB
Unconjugated
100µl  $425.00
IHC using MBP Antibody (2H9)
IHC using MBP Antibody (2H9)
IHC using MBP Antibody (2H9)
IHC using MBP Antibody (2H9)

MBP / Myelin Basic Protein Antibody (aa182-197) LS-C171775
Rabbit Polyclonal to Human MBP / Myelin Basic Protein
Mouse, Rat, Human
IHC WB
Unconjugated
100µg 0.5mg/ml  $295.00
Immunohistochemistry Image
Western blot Image
Immunohistochemistry Image
Western blot Image

MBP / Myelin Basic Protein Antibody LS-C41683
Rabbit Polyclonal (IgG) to Human MBP / Myelin Basic Protein
Rat, Human
ELISA WB
Unconjugated
1000µl 1mg/ml  $325.00

MBP / Myelin Basic Protein Antibody (clone 5F12-B10) LS-C63078
Mouse Monoclonal [clone 5F12-B10] (IgG1) to Human MBP / Myelin Basic Protein
IP WB
Unconjugated
100µg 1mg/ml  $375.00

MBP / Myelin Basic Protein Antibody LS-C678592
Rabbit Polyclonal (IgG) to Human MBP / Myelin Basic Protein
Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry Dilution at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry Dilution at 1:400 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry Dilution at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry Dilution at 1:400 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.

MBP / Myelin Basic Protein Antibody (aa69-86) LS-C25714
Rabbit Polyclonal (IgG) to Guinea pig MBP / Myelin Basic Protein
Guinea pig, Rat, Human
IHC
Unconjugated
50µl  $680.00

MBP / Myelin Basic Protein Antibody LS-C660330
Rabbit Polyclonal (IgG) to Human MBP / Myelin Basic Protein
Human
ELISA IF IHC WB
Unconjugated
100µg  $405.00

MBP / Myelin Basic Protein Antibody (phospho-Thr98) LS-C124203
Mouse Monoclonal (IgG2a) to Human MBP / Myelin Basic Protein
Human
ELISA IHC IHC-Fr IHC-P WB
Unconjugated
100µg  $650.00

MBP / Myelin Basic Protein Antibody LS-C331626
Rabbit Polyclonal (IgG) to Human MBP / Myelin Basic Protein
Mouse, Rat, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded rat kidney using MBP antibodyat dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using MBP antibodyat dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using MBP antibodyat dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using MBP antibodyat dilution of 1:200 (40x lens).

MBP / Myelin Basic Protein Antibody (aa82-91) LS-C25711
Mouse Monoclonal (IgG2a) to Bovine MBP / Myelin Basic Protein
Bovine
ELISA IHC IHC-Fr WB
Unconjugated
250µl  $575.00

MBP / Myelin Basic Protein Antibody (aa82-91) LS-C44007
Mouse Monoclonal (IgG2a) to Bovine MBP / Myelin Basic Protein
Bovine
ELISA IHC IHC-Fr WB
Unconjugated
250µl  $385.00

MBP / Myelin Basic Protein Antibody LS-C122172
Mouse Monoclonal (IgG2b) to Human MBP / Myelin Basic Protein
Human
IHC IHC-Fr IHC-P WB
Unconjugated
2000µl  $605.00
Showing 1-25 of 150 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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