Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey (tested or 100% immunogen sequence identity)
Mouse, Rat, Bat, Bovine, Dog, Horse, Rabbit (at least 90% immunogen sequence identity)
Western blot (1:16000) & (0.1 - 0.3 µg/ml)
IHC - Paraffin
Specificity and Use
LYN antibody was raised against synthetic peptide C-KTQPVRNTERT from an internal region of human LYN (NP_002341.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (100%); Mouse, Rat, Dog, Bovine, Bat, Horse, Rabbit, Opossum (91%); Elephant, Platypus (82%).
LS-E26666 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55075. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. Functions primarily as negative regulator, but can also function as activator, depending on the context.