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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LOX / Lysyl Oxidase Antibody (aa234‑260) LS‑C165844
Lysyl Oxidase antibody LS-C165844 is an unconjugated rabbit polyclonal antibody to human Lysyl Oxidase (LOX). Validated for Flow and WB.
Catalog
Size
Price
LS-C165844-400
400 µl
Unavailable

Popular LOX / Lysyl Oxidase Products

Human placental villi, 40X. Staining of placental trophoblasts using antibody at 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Bovine, Pig
Applications: IHC, IHC - Paraffin, Western blot
LOX propeptide Antibody - IHC of LOPP in mouse intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Rat, Pig, Primate
Applications: IHC, IHC - Paraffin
Western blot of LOX in A) human skin and B) mouse ear skin lysate using LS-C148572 at 1:500. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.
Species: Human, Monkey, Mouse, Bat, Rabbit
Applications: IHC, IHC - Frozen, Western blot, Immunoprecipitation
Anti-Lysyl Oxidase / LOX antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8037 dilution 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Rat
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-LOX mouse monoclonal antibody.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry

Product Description

Lysyl Oxidase antibody LS-C165844 is an unconjugated rabbit polyclonal antibody to human Lysyl Oxidase (LOX). Validated for Flow and WB.
About LOX / Lysyl Oxidase
Lysyl Oxidase / LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). P28300 NM_002317 NP_002308.2

LOX Antibody, Lysyl oxidase Antibody, Protein-lysine 6-oxidase Antibody


Specifications

Target
Human LOX / Lysyl Oxidase
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)
Blocking Peptide
LS-E9955 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C165844. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa234-260
Specificity
This LOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


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Images


Western blot

Western blot of LOX Antibody in MDA-MB468 cell line lysates (35 ug/lane). LOX (arrow) was detected using the purified antibody.
Western blot of LOX Antibody in MDA-MB468 cell line lysates (35 ug/lane). LOX (arrow) was detected using the purified antibody.

Flow Cytometry

LOX Antibody flow cytometry of 293 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
LOX Antibody flow cytometry of 293 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot

Western blot of LOX Antibody in MDA-MB468 cell line lysates (35 ug/lane). LOX (arrow) was detected using the purified antibody.
Western blot of LOX Antibody in MDA-MB468 cell line lysates (35 ug/lane). LOX (arrow) was detected using the purified antibody.

Flow Cytometry

LOX Antibody flow cytometry of 293 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
LOX Antibody flow cytometry of 293 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot

Western blot of LOX Antibody in MDA-MB468 cell line lysates (35 ug/lane). LOX (arrow) was detected using the purified antibody.
Western blot of LOX Antibody in MDA-MB468 cell line lysates (35 ug/lane). LOX (arrow) was detected using the purified antibody.

Flow Cytometry

LOX Antibody flow cytometry of 293 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
LOX Antibody flow cytometry of 293 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot

Western blot of LOX Antibody in MDA-MB468 cell line lysates (35 ug/lane). LOX (arrow) was detected using the purified antibody.
Western blot of LOX Antibody in MDA-MB468 cell line lysates (35 ug/lane). LOX (arrow) was detected using the purified antibody.

Flow Cytometry

LOX Antibody flow cytometry of 293 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
LOX Antibody flow cytometry of 293 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.


Requested From: 
Date Requested: 6/20/2018

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