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Anti-LIN28A / LIN28 Antibody (phospho-Ser134) LS-C163637

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular LIN28A / LIN28 Antibodies

Anti-LIN28A / LIN28 Antibody (aa100-150) LS-C148680
Rabbit Polyclonal to Human LIN28A / LIN28
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-LIN28A / LIN28 Antibody (aa108-138) IHC-plus™ LS-B11566
Rabbit Polyclonal to Human LIN28A / LIN28
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human LIN28A / LIN28
Human
ICC, Immunofluorescence, Dot Blot
Unconjugated

Details

Human LIN28A / LIN28
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • ICC
  • Immunofluorescence (1:100)
  • Dot Blot (1:500)

Specificity and Use

LIN28A / LIN28 antibody was raised against kLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S134 of human LIN28.
LS-E7473 - Lyophilized - 100 µg - $145.00
pSer134
Human LIN28A / LIN28

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About LIN28A / LIN28

Q9H9Z2 NM_024674 NP_078950.1

LIN28A Antibody, CSDD1 Antibody, Lin-28 homolog (C. elegans) Antibody, LIN-28 Antibody, Lin-28A Antibody, LIN28 Antibody, Protein lin-28 homolog A Antibody, Lin-28 homolog A (C. elegans) Antibody, ZCCHC1 Antibody, RNA-binding protein LIN-28 Antibody

Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA.

Immunofluorescence

Immunofluorescence
Fluorescent confocal image of SY5Y cells stained with phospho- LIN28- S134 antibody. SY5Y cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.2%, 30 min). Cells were then incubated phospho- LIN28- S134 primary antibody (1:100, 2 h at room temperature). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:1000, 1h). Nuclei were counterstained with Hoechst 33342 (blue) (10 ug/ml, 5 min). Note the highly specific localization of the phospho- LIN28 immunosignal mainly to the nucleus, supported by Human Protein Atlas Data (http://www.proteinatlas.org/ENSG00000131914).

Dot Blot

Dot Blot
Dot blot of anti-Phospho-LIN28-S134 Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Requested From: United States
Date Requested: 12/9/2016

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