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Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.
Gene Name: | LIM domain binding 1 |
Synonyms: | LDB1, CLIM-2, HLdb1, LIM domain-binding factor-1, LIM domain-binding protein 1, NLI, LIM domain binding 1, CLIM2, LDB-1, Nuclear LIM interactor |
Target Sequences: | NM_003893 NP_003884.1 Q86U70 |
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