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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LCX / TET1 Antibody (Biotin) LS‑C180924
Antibody
TET1 antibody LS-C180924 is a biotin-conjugated rabbit polyclonal antibody to mouse TET1 (LCX). Validated for IHC.
Catalog
Size
Price
LS-C180924-100
100 µl (1.07 mg/ml)
Unavailable

Popular LCX / TET1 Products

Western blot analysis of extracts of A431 cell lines.
Species: Human, Mouse, Rat
Applications: Western blot, Immunoprecipitation
IHC of paraffin-embedded Human tonsil using anti-TET1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Species: Human
Applications: IHC, IHC - Paraffin
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Anti-Tet1 Antibody at 1:2000 dilution + F9 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 219 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Species: Mouse
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Paraffin-embedding Immunohistochemistry using human colon cancer at dilution 1:100
Species: Human
Applications: IHC, ELISA

Product Description

TET1 antibody LS-C180924 is a biotin-conjugated rabbit polyclonal antibody to mouse TET1 (LCX). Validated for IHC.
About LCX / TET1
Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Q8NFU7 NM_030625 NP_085128.2

TET1 Antibody, CXXC6 Antibody, CXXC finger 6 Antibody, Tet oncogene 1 Antibody, BA119F7.1 Antibody, CXXC zinc finger 6 Antibody, KIAA1676 Antibody, LCX Antibody, Ten-eleven translocation-1 Antibody


Specifications

Target
Human LCX / TET1
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with DY650, DY488, DY550.
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:400)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • ICC
  • Western blot
Immunogen
LCX / TET1 antibody was raised against a synthetic peptide made to an internal portion of the human TET1 protein (between residues 170-800) [UniProt Q8NFU7].
Specificity
Staining is observed in the in the nucleus and cytoplasm of mouse spleen tissue.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.05% sodium azide
Storage
Store at 4°C in the dark.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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