Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Guinea pig Polyclonal (IgG) to Rat KRT86 / Keratin 86 / KRTHB6
IHC - Frozen, Western blot
KRT86 / Keratin 86 / KRTHB6
Rat, Mouse (tested or 100% immunogen sequence identity)
IHC - Frozen
Western blot (1:2000)
Specificity and Use
KRT86 / Keratin 86 / KRTHB6 antibody was raised against basic hair keratin hHb6.
Stains specifically human hair keratin hHb6 expressed starting from the middle hair cortex. It can be defect in monilethrix. Reactive with human and mouse.
Suitable for use in Immunohistochemistry and Western Blot. Immunohistochemistry (frozen): 1:200. Preincubate fixed sections with 0.1 Triton X-10 (in PBS) for 1-5 min prior to 1 hour incubation. Western Blot: 1:2000. Incubate for 1 hour at RT.
0.09% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
KRT86 Antibody, HB1 Antibody, HHb6 Antibody, Keratin protein HB6 Antibody, Keratin 86 Antibody, Keratin, type II cuticular Hb6 Antibody, K86 Antibody, Keratin-86 Antibody, KRTHB6 Antibody, MNX Antibody, Type II hair keratin Hb6 Antibody, Type-II keratin Kb26 Antibody, Hair keratin K2.11 Antibody, Hard keratin, type II, 6 Antibody, HB6 Antibody, KRTHB1 Antibody
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.