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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KRT18 / CK18 / Cytokeratin 18 Antibody (clone DC‑10, Biotin) LS‑C46259
Antibody
Cytokeratin 18 antibody LS-C46259 is a biotin-conjugated mouse monoclonal antibody to human Cytokeratin 18 (KRT18 / CK18). Validated for Flow.
Catalog
Size
Price
LS-C46259-100
100 µg (1 mg/ml)
Unavailable

Popular KRT18 / CK18 / Cytokeratin 18 Products

Antibody
Species: Human, Mammal
Applications: Flow Cytometry
Anti-KRT18 / Cytokeratin 18 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1669 dilution 1:50.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen
Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human prostate, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Anti-KRT18 / CK18 / Cytokeratin 18 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9908 concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mammal
Applications: IHC, IHC - Paraffin, Flow Cytometry

Product Description

Cytokeratin 18 antibody LS-C46259 is a biotin-conjugated mouse monoclonal antibody to human Cytokeratin 18 (KRT18 / CK18). Validated for Flow.
About KRT18 / CK18 / Cytokeratin 18
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. P05783 NM_000224 NP_000215.1

KRT18 Antibody, CK-18 Antibody, Cytokeratin 18 Antibody, Cytokeratin-18 Antibody, K18 Antibody, Keratin 18 Antibody, CYK18 Antibody, Keratin-18 Antibody


Specifications

Target
Human KRT18 / CK18 / Cytokeratin 18
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [DC-10]
Conjugations
Biotin. Also available Unconjugated.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Flow Cytometry (1:500)
  • (applications tested for the base form of this product only)
Immunogen
Human breast carcinoma cell line PMC-42.
Specificity
Reacts with Cytokeratin 18 (45 kD). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
Usage
The reagent is designed for Flow cytometry. Suggested working dilution is 1:500. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 15 mM sodium azide, approx., pH 7.4.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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