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Anti-KLRK1 / CD314 / NKG2D Antibody LS-C44803

Note: This antibody replaces LS-C57936

Ordering

Wt. Vol. Conc. Price
200 µg - 1 mg/ml $370
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular KLRK1 / CD314 / NKG2D Antibodies

Anti-KLRK1 / CD314 / NKG2D Antibody (aa136-147) LS-C20184
Goat Polyclonal to Human KLRK1 / CD314 / NKG2D
Human, Monkey
Western blot, ELISA
Unconjugated
Western blot Image
Anti-KLRK1 / CD314 / NKG2D Antibody (clone 1D11) LS-C123953
Mouse Monoclonal [clone 1D11] (IgG1) to Human KLRK1 / CD314 / NKG2D
Human
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-KLRK1 / CD314 / NKG2D Antibody (clone 1D11, FITC) LS-C204417
Mouse Monoclonal [clone 1D11] (IgG1) to Human KLRK1 / CD314 / NKG2D
Human
Flow Cytometry
FITC Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human KLRK1 / CD314 / NKG2D
Human
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated

Details

Human KLRK1 / CD314 / NKG2D
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:100)

Specificity and Use

KLRK1 / CD314 / NKG2D antibody was raised against nKL cells.
Specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding toCD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
For research use only.

About KLRK1 / CD314 / NKG2D

P26718 NM_007360 NP_031386.2

KLRK1 Antibody, D12S2489E Antibody, CD314 antigen Antibody, KLR Antibody, NK cell receptor D Antibody, NKG2D Antibody, NKG2-D Antibody, NKG2-D-activating NK receptor Antibody, CD314 Antibody

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.

Requested From: United States
Date Requested: 12/5/2016

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