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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ITGAM / CD11b Antibody (clone ICRF44) LS‑C204381
Antibody
CD11b antibody LS-C204381 is an unconjugated mouse monoclonal antibody to CD11b (ITGAM) from human and primate. Validated for Block, Flow, Func, ICC, IHC, IP and Neut.
Catalog
Size
Price
LS-C204381-100
100 µg (1 mg/ml)
Unavailable

Popular ITGAM / CD11b Products

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Product Description

CD11b antibody LS-C204381 is an unconjugated mouse monoclonal antibody to CD11b (ITGAM) from human and primate. Validated for Block, Flow, Func, ICC, IHC, IP and Neut.
About ITGAM / CD11b
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. P11215 NM_000632 NP_000623.2

ITGAM Antibody, Antigen CD11b (p170) Antibody, CD11B Antibody, CD11b antigen Antibody, CR3A Antibody, Integrin alpha-M Antibody, MAC-1 Antibody, MO1A Antibody, Neutrophil adherence receptor Antibody, MAC1A Antibody, SLEB6 Antibody, CR-3 alpha chain Antibody


Specifications

Target
Human ITGAM / CD11b
Host
Mouse
Reactivity
Human, Primate (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [ICRF44]
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • ICC
  • Immunoprecipitation
  • Flow Cytometry
  • Blocking
  • Functional Assay
  • Neutralization
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ITGAM / CD11b antibody was raised against rheumatoid synovial cells and human monocytes.
Specificity
Monoclonal antibody ICRF44 recognizes CD11b (Mac-1alpha), a 165-170 kD type 1 transmembrane protein mainly expressed on monocytes, granulocytes and NK-cells.
Usage
Functional Application: blocking of granulocyte activation.
Presentation
PBS, pH 7.4, sterile filtered.
Storage
Store at 2-8°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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