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The integrin alpha-1 chain associates with the integrin beta-1 chain to form a heterodimeric cell surface unit that functions as a receptor for laminin and collagen in neural cells and hematopoietic cells. It is involved in cell adhesion and neurite outgrowth. It may also play a role in inflammation and fibrosis.
Gene Name: | integrin, alpha 1 |
Family/Subfamily: | Integrin , not assigned-Integrin |
Synonyms: | ITGA1, CD49a antigen, CD49a, Integrin Alpha 1, Integrin, alpha 1, Integrin alpha-1, Laminin and collagen receptor, Very late activation protein 1, VLA1, VLA-1 |
Target Sequences: | NM_181501 NP_852478.1 P56199 |
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